Written by Suryana Purawisastra, Erwin Affandi
Abstract. The high level of blood cholesterol is one of the risk factor for artherosclerotic cardiovascular disease. The number of people suffering from cardiovascular disease as the consequence of their life style, particularly in the city. On the other hand, it was reported that dietary fiber supplementation could inhibit the increase of the blood cholesterol level. One of these dietary fibers known as galactomannan found sufficiently in the residue of coconut kernel. This study was to prove the effect of this dietary fiber supplementation to the increased level of the blood cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglyceride, in the rabbit experiment. The result of the study shown that the effect of supplemention of galactomannan dietary fiber of the coconut kernel to the cholesterol level was in the form of isolated galactomanan. In 26 days, the isolated galactomannan reduced the cholesterol level by 12 mg/dl (p=0.069), 10 mg/dl (p=0.231) of the LDL, and 7 mg/dl (p=0.138) of the triglyceride. The HDL level raised 1 mg/dl (p=0.021). The inhibitation raises significantly when the supplemetation was continued for 52 days. There were an increase of 24 mg/dl (p=0.010) for cholesterol, 15 mg/dl for LDL (p=0.045), 18 mg/dl (p=0.015) for triglyceride. Whereas the increase of the HDL level remained in 1 mg/dl (p= 0.032). The conclusion of this study was that the effect of supplemention of galactomannan dietary fiber contained in the coconut kernel to the cholesterol, trigliseride was in the form of the isolated galactomannan. It could be suggested that the isolated galactomannan produced from the residue of coconut kernel was becoming an alternatif food supplementation for reducing the choletserol level of hyperlipidemia.
Keywords: Dietary fiber, galactomannan, cholesterol, coconut, and experimental animal.
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