Written by Sarwo Handayani
Abstract. Research and routine survey of meningococcal meningitis on Indonesian hajj pilgrims have been conducted since 1993 until now. This paper consists of several research and routine survey of meningococcal meningitis during 1993 and 2003. The objectives of the test were determining the meningococcal meningitis carrier on hajj pilgrims, determining the serogroup of N. meningitidis and knowing sensitivity of bacteria to several antibiotics. The result showed increasing of meningococcal meningitis carrier in 1993 up to 1996, that was 1.3% - 9,4% respectively. This proportion of meningococcal meningitis carrier in the case groups decreased after given of rifampicin in 1994 and cyprofloxacin in 1997 as a chemoprophilactic The result of the study in 1997 indiciated that the carrier rate of groups with cyprofloxacin (1.4%) was lower than rifampicin group (14%). Most of the isolated bacteria of N. meningitidis in 1996 and 1997 were resistant to rifampicin (sensitivity test was 0-33%). Serogroup B of N. meningitidis were found dominantly between 1993 and 1999, it changed to be serogroup W135 from 2000 to 2003. The changes related with the majority cases of meningococcal meningitis in another countries that caused by serogroup W135. Because of that since 2002, immunization program has given a tetravalen (serogroup ACYW135) meningococcal vaccine to all of Indonesian haj pilgrims. The carrier of meningococcal meningitis is still found in haj pilgrims and their contact. More attention must be given, caused of meningococcal meningitis serogroup B vaccine is not available. The further researches are needed especially for subtype of N. meningitidis, effectivity of the drug choice and development of meningococcal meningitis vaccine serogroup B.
Key word: meningitis, Neisseria meningitidis, vaccine
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